For all six drugs, the limits of quantification ranged between 6 and 12 pg/mg. The intra-day and inter-day coefficients of variation were within 15%, and the recoveries ranged from 91.1% to 113.7%. Furthermore, the other validation parameters (i.e., selectivity, matrix effect, stability, and carryover) met the acceptance criteria stipulated by guidelines of the United States Food and Drug...

Salivary CRP could be used as an alternative bio-marker of neonatal sepsis. To review the clinical outcome and electrophysiologic characteristics of children with Guillain-Barre syndrome (GBS) from Eastern India. The hospital records of the children aged less than 12 years with a final diagnosis of GBS at our hospital from November, 2015 to December, 2018 were reviewed. Disabilities were...

Superior semicircular canal dehiscence (SSCD) syndrome was first reported in 1998 by Minor et al. and comprises a spectrum of auditory and vestibular symptoms as a result of 'mobile third window' mechanism. The aetiology of SSCD is debated, but persistent infantile microstructure of the temporal bone was suggested. However, some authors related a 'second event', such as closed head trauma,...

It is estimated that approximately one-tenth of the US population suffers from substance use disorders (SUD), a problem that is compounded when one considers the impact that drug addiction could have on treatment outcomes for many other chronic diseases. Thus, addiction medicine has become an important component of many successful urban primary care practices and residencies across the country....

Shofu Hard and Cerasmart (>93%) demonstrated no significant difference for any calculated mission (300-800 N). Failure mode predominantly involved resin-matrix ceramic fracture originated from occlusal cracks, corroborating with the MP Stress and Strain location, propagating through the proximal and cervical margins. All resin-matrix ceramics crowns demonstrated high probability of survival...