Market Highlights

According to MRFR analysis, the global chromatography columns market is expected to register a CAGR of ~5.8% from 2021 to 2027 and hold a value of over ~USD 16,320 millionin 2027.

The global chromatography columns market is driven by several factors, suchas an increase in life science R&D expenditure anda rise in the production of monoclonal antibodies. For instance, in 2020, the National Institutes of Health (NIH) received funding of USD 42 billion, which was an increase of 7% compared to 2019. Furthermore, the rising demand for biopharmaceutical products due to the increasing prevalence of communicable and non-communicable diseases also supplements the market growth. However, the lack of skilled professionals in the market may lead to growth restraints during the forecast period.

The industry players are focusing on new product development and launches to enter the global Chromatography Columns Market Trends. For instance, in March 2019, KNAUER WissenschaftlicheGeräte GmbH (Germany)launched new protein purification liquid chromatography columns and media that can be utilized for affinity, size-exclusion, and ion-exchange (IEX) chromatography. Furthermore, the key players are involved in acquisitions, strategic agreements, and joint ventures to augment their market positions. For instance,in January 2021, Sartorius AG (Germany) entered into an agreement to acquire Novasep, Inc.’s (France) chromatography process equipment division to provide a stronger product portfolio.

Key Players

Some of the key players in the global chromatography columns market are Merck KGaA (Germany), Thermo Fisher Scientific Inc. (US), Agilent Technologies, Inc. (US), Daicel Corporation (Japan), Shimadzu Corporation (Japan), PerkinElmer Inc. (US), Bio-Rad Laboratories, Inc. (US), Biotage (Sweden), Waters (US), KNAUER WissenschaftlicheGeräte GmbH (Germany), and Tosoh Corporation (Japan)among others.

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Regional Analysis

North Americais likely to dominate the chromatography columns market in 2020, owing to the presence of key players, increasing investments in R&D, and rising drug development activities in the region. For instance, in 2020, the National Institutes of Health (NIH) was funded with USD 42 billion, which was an increase of7% compared to 2019.

Europeis likely to account for a significant share in the chromatography columns market due to supportive government initiations and rising R&D investments. For instance, the EU had set up the Horizon 2020 with a funding of around USD 95 billion for research and innovations, which ran from 2014 to 2020.

Asia-Pacific is anticipated to be the fastest-growing market during the forecast period due to improving healthcare infrastructure, increasing R&D expenditure, and rising disease burden in the region. For instance, according to the Cancer Council of Australia, around 150,000 new cancer cases were diagnosed, along with around 50,000 deaths were recorded in 2020. Moreover, according to World Cancer Research Fund (WCRF), in 2018, Australia had the highest cancer rate in the world for both sexes at 468.0 per 100,000 individuals. Furthermore, signifying the increase in research spending, according to Statista (Germany), China will surpass the US in R&D expenses in 2021 with an estimated USD 621 billioninvestment compared to USD 598.7 billion by the US.

Furthermore, the growth of the market in the rest of the world is expected to grow at the least CAGR due to low R&D expenditure and inadequate healthcare infrastructure. However, factors such as government initiatives to bring in technological advancements and expansion of R&D capabilities in the region by global players are expected to provide growth for the market in the region during the forecast period.


The global chromatography columns market has been segmented into column type, chromatography type, application, and end user.

By column type, the market has been segmented into normal phase chromatography columns, pre-packed chromatography columns, and automated chromatography columns. The pre-packed chromatography columnssub-segment is expected to hold the largest market share in 2021 due to its ease and time-saving capabilities.

By chromatography type, the market has been segmented into ion-exchange chromatography, affinity chromatography, gas chromatography, size exclusion chromatography, and others. The affinity chromatography segment is expected to holdthe largestshare in 2020 as it is the first step for purification for several molecules such as proteins and monoclonal antibodies, hence high in demand.

By application, the market has been segmented into anion and cation exchange, sample preparation, resin screening, protein purification, and desalting. The protein purification segment is expected to hold the major share in 2021 due to advancements in protein engineering and proteomics.

Based on end users, the market has been segmented into research institutes, pharmaceutical biotechnology companies, food & beverage manufacturers, and others. The pharmaceutical biotechnology companies segmentheld the largest segment share in 2020, owing to the use of chromatography columns in their extensive R&D efforts and funding put in by pharmaceutical biotechnology companies to develop new therapeutics, along withthe production of their existing therapeutics.

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