Biologics Contract Manufacturing Market: Introduction

According to the report, the global biologics contract manufacturing market was valued at US$ 13.3 Bn in 2020 and is projected to expand at a CAGR of 12.2% from 2021 to 2031. Biologics is the application of biotechnology to medicine. These are mostly produced from cell lines and are portentous molecules. Biologics are used in the treatment, diagnosis, or prevention of diseases such as cancer and diabetes.

Biologics are manufactured in a living system such as plant cell, animal cell, or microorganisms. These are complex molecules and produced by recombinant technology. Biologics include proteins such as hormones, vaccines, monoclonal antibodies, etc. The global biologics contract manufacturing market is driven by increase in investment in research & development activities and rise in prevalence of chronic diseases.

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Growth of Biopharmaceutical Industry and Promising Drug Pipeline

Increase in biopharmaceutical sales and promising drug pipeline drive the overall need of biologics clinical development and manufacturing services across the whole spectrum, from pre-clinical services to commercial manufacturing. Over 3,500 recombinant proteins and antibodies are in pre-clinical and clinical trials, including treatments that have been approved. An increasing number of molecules are being developed by small and virtual biotech companies. These companies do not have the in-house manufacturing capacity and expertise to bring their candidates to market, and therefore have a higher propensity to outsource. Presently, these emerging biopharma companies constitute around 80% of the development pipeline.

Increase in Adoption of Monoclonal Antibodies

In terms of type, the global biologics contract manufacturing market has been classified into monoclonal antibodies, recombinant proteins, vaccines, molecular therapy and others (RNAi, antisense RNA, etc.). The monoclonal antibodies segment was valued at US$ 5.6 Bn in 2020 and is projected to reach US$ 18.9 Bn by 2031, expanding at a CAGR of 11.7% from 2021 to 2031. The segment’s dominance can be attributed to increase in adoption of monoclonal antibodies for large unmet medical needs in the fields of oncology and autoimmune disorders.

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North America to Lead Biologics Contract Manufacturing Market

In terms of region, the global biologics contract manufacturing market has been segmented into North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. The biologics contract manufacturing market in North America was valued at US$ 5.8 Mn in 2020 and is projected to reach US$ 19.5 Bn by 2031, expanding at a CAGR of 11.7 % from 2021 to 2031. The pharmaceutical industry in North America has long been a significant player in the global market for new biologics. Anticancer drugs, as well as enhanced immune class drugs, have been at the forefront of the region’s biopharmaceutical product development, including cutting-edge technologies such as checkpoint inhibitors (e.g. PD1), chimeric antigen receptor (CAR)-T-cell therapies, antibody drug conjugates (ADCs), and monoclonal antibodies (mAbs).

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Competition Landscape

The global biologics contract manufacturing market is fragmented due to the presence of a large number of leading players. Key players operating in the global market include Lonza Group, Samsung Biologics Co., Ltd., Patheon by Thermo Fisher Scientific, Inc., Cambrex Corporation, Siegfried Holding AG, Fujifilm Holding Corporation, AbbVie, Inc., Boehringer Ingelheim, Recipharm Pharmaceuticals, Catalent, Inc., and Wuxi Biologics.

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