The Global Cell Line Development Market size was valued at USD 6.74 billion in 2021 and is projected to reach USD 12.09 billion by 2028, growing at a CAGR of 8.7% from 2022 to 2028.

Cell line development can be performed using a variety of expression systems, including bacterial, plant, yeast and mammalian expression systems. Chinese Hamster Ovary (CHO) cells, grown at the production stage in suspension culture for primary use in bioreactors, are most commonly used for the production of complex proteins. In recent years, molecular tools such as zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and, more recently, the CRISPR / Cas9 system have improved gene editing. When it comes to developing cell lines for optimal biotherapeutic performance, these strategies lead to accuracy and ease of use.

In addition, the increased production of biosimilars due to the expiration of the patent for branded therapies and recombinant proteins is expected to increase demand. Over the projection horizon, the growing prevalence of chronic diseases will require better therapeutic solutions and will increase the demand for biosimilars, vaccines, therapeutic proteins and new drugs. Human cell lines used in vaccine production include the US developed WI-38 cell line and the UK developed MRC-5 cell line.

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The Major Players in The Global Cell Line Development Market:

  • GE Healthcare
  • Sartorious AG
  • Corning Inc.
  • WuXi AppTec Inc.
  • Selexis SA
  • Sigma-Aldrich Corporation
  • Lonza Group AG
  • Sartorius
  • Thermo Fisher Scientific Inc.
  • Danaher Corporation
  • Merck KGaA
  • Promega Corporation
  • Beckman Coulter Inc.
  • European Collection of Cell Cultures

Market has segmented the Global Cell Line Development Market on the basis of type, application, and region:

By Product :

  • Equipment
  • Reagents & Media
  • Accessories & Consumables

By Application:

  • Bioproduction
  • Drug Discovery
  • Toxicity Testing
  • Tissue Engineering
  • Research

 

By Regional Outlook (Revenue, USD Billion, 2022 – 2028)

  • North America (U.S., Canada, Mexico)
  • Europe (Germany, U.K., France, Italy, Russia, Spain, Rest of Europe)
  • Asia-Pacific (China, India, Japan, Southeast Asia, Rest of APAC)
  • Middle East & Africa (GCC Countries, South Africa, Rest of MEA)
  • South America (Brazil, Argentina, Rest of South America)

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Covid-19 Impact and Recovery Analysis on Industry:

Johnson & Johnson used this cell line to create the COVID-19 vaccine. These cells were used to grow adenoviruses that had been modified so that they would not replicate or cause disease, which was then purified and used to deliver the genetic code for SARS-CoV-2's signature spike protein. The J&J vaccine does not contain any of the adenoviruses.

Pfizer and Moderna used HEK-293, an immortal cell line derived from the kidney of an aborted fetus in the 1970s for the production of its COVID-19 vaccine. During development, the cells were used to confirm that the genetic instructions for producing the SARS-CoV-2 spike protein worked in human cells. According to Alessondra Speidel, the cell lines were used as a proof-of-concept test, and neither of these mRNA vaccines was produced using fetal cells.

Reasons to purchase the report:

  • Visualize the composition of the Global Cell Line Development Market products in terms of Product and application highlighting the critical commercial assets and players.
  • Identify commercial opportunities in the Global Cell Line Development Market by analyzing trends and co-development deals.
  • PDF report with the most relevant analysis cogently put together after exhaustive qualitative interviews and in-depth market study.

Table of Content:

Chapter 1: Introduction
 1.1 Research Objectives
 1.2 Research Methodology
 1.3 Research Process
 1.4 Scope and Coverage
  1.4.1 Market Definition
  1.4.2 Key Questions Answered
 1.5 Market Segmentation

Chapter 2:Executive Summary

Chapter 3:Growth Opportunities By Segment
 3.1 By Product
 3.2 By Source
 3.3 By Cell Line Type
 3.4 By Application

To be continued…….

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