What is bone edema: diagnosis, causes and treatments? The bone edema is swelling of the inner area of the bone, called the medulla. This inflammation can occur for different reasons such as a large blow or excessive physical load, but it can also happen as a result of repetitive micro-trauma. If it is not treated and is prolonged in time, it can lead to irreversible injuries. It is essential that if you suffer from acute and localized pain in the...